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President Bush nominates the head of one of Wall Street's top financial firms to lead the Treasury Department. Henry Paulson Jr. -- chairman of Goldman Sachs -- is slated to replace resigning Secretary John Snow. The White House hopes Paulson will do a better job than Snow selling the president's economic record.

Conditions are worsening in Myanmar as hungry survivors wait among the dead for help after a huge cyclone hit the Southeast Asian nation over the weekend. The top U.S. diplomat in the country is predicting that the death toll could rise as high as 100,000, from the official tally of 22,500.

Will John McCain go over the top? Would an Obama sweep get Clinton out of the race? Or does a Clinton victory in either state — or both — keep the battle going on to Pennsylvania on April 22? Robert Siegel talks with NPR's Mara Liasson about what to look for in Tuesday's primary elections in Texas and Ohio.

What do UFOs, Fireball Cinnamon and a dead snowshoe hare have in common? They all made the list of NPR.org's top stories of the year.

Known for his intellectual and illuminating touch on the podium, the refined conductor was also surprisingly outspoken when it came to politics and his peers.

On Wild Card, well-known guests answer the kinds of questions we often think about but don't talk about. Padma Lakshmi reflects on the lessons her grandmother taught her through cooking.

NPR's Rachel Martin speaks with WGBO jazz expert Nate Chinen about his interview with Lady Gaga about her new album with Tony Bennett, Love for Sale.

Backstreet Boys members Brian Littrell and AJ McLean joined NPR's Audie Cornish-Emery to talk about what fans can expect on the group's upcoming album, DNA.

The Oscar-nominated Iranian screenwriter Mehdi Mahmoudian was arrested after condemning the regime's crackdown on protesters, which director Jafar Panahi says represents the actions of a "failed state."

Here's what we know about the speech, the guests and the stakes for this election-year State of the Union address.